2B-Alert Web
Predict the effects of sleep/wake and caffeine on alertness
This software tool predicts alertness of an "average" individual as a function of sleep/wake schedule and caffeine consumption. Specifically, this tool allows users to manually enter a sleep/wake schedule and caffeine dosing and timing, and displays the corresponding predictions for three different psychomotor vigilance task alertness statistics.

This tool can be used to:
  1. Assess the effect of different sleep/wake schedules and caffeine consumption
  2. Design sleep/wake and caffeine schedules to optimize alertness
  3. Generate hypotheses that can be experimentally tested
Disclaimer: The 2B-Alert Web tool is for educational and informational purposes only. It should not be used for or relied upon for predicting the performance of any specific individual or the likelihood of errors or accidents by any specific individual or a group of individuals.

Key References:
  1. Rajdev, P., D. Thorsley, S. Rajaraman, T. L. Rupp, N. J. Wesensten, T. J. Balkin, and J. Reifman. A unified mathematical model to quantify performance impairment for both chronic sleep restriction and total sleep deprivation. Journal of Theoretical Biology. 2013 April 24; 331:66-77. (PubMed ID: 23623949)
  2. Ramakrishnan, S., S. Laxminarayan, N. J. Wesensten, G. H. Kamimori, T. J. Balkin, and J. Reifman. Dose-dependent model of caffeine effects on human vigilance during total sleep deprivation. Journal of Theoretical Biology. 2014 October 7; 358:11-24. (PubMed ID: 24859426)
  3. Ramakrishnan, S., N. J. Wesensten, T. J. Balkin, and J. Reifman. A unified model of performance: validation of its predictions across different sleep/wake schedules. Sleep. 2016 January 1; 39(1):249-262. (PubMed ID: 26518594)
  4. Ramakrishnan, S., N. J. Wesensten, G. H. Kamimori, J. E. Moon, T. J. Balkin, and J. Reifman. A unified model of performance for predicting the effects of sleep and caffeine. Sleep. 2016 October 1; 39(10):1827-1841. (PubMed ID: 27397562)
  5. Reifman, J., K. Kumar, N. J. Wesensten, N. A. Tountas, T. J. Balkin, and S. Ramakrishnan. 2B-Alert Web: An open-access tool for predicting the effects of sleep/wake schedules and caffeine consumption on neurobehavioral performance. Sleep. 2016 December 1; 39(12):2157-2159. (PubMed ID: 27634801)
Cite 2B-Alert Web as:

Reifman, J., K. Kumar, N. J. Wesensten, N. A. Tountas, T. J. Balkin, and S. Ramakrishnan. 2B-Alert Web: An open-access tool for predicting the effects of sleep/wake schedules and caffeine consumption on neurobehavioral performance. Sleep. 2016 December 1; 39(12):2157-2159.

© 2017 BHSAI
Version 1.0.1